Duplication and Nuclear Envelope Insertion of the Yeast Microtubule Organizing Centre, the Spindle Pole Body
The main microtubule organizing centre in the unicellular model organisms Saccharomyces cerevisiae and Schizosaccharomyces pompe is the spindle pole body (SPB).The SPB is a multilayer structure, which duplicates exactly once per cell cycle.Unlike higher eukaryotic cells, both yeast model organisms undergo mitosis without breakdown of the nuclear en